Hauv kev tshawb fawb tsis ntev los no tau luam tawm nyob rau hauv phau ntawv Journal Scientific Reports, ob-dimensional biocompatible thiab elastic plasmonic contact lo ntsiab muag tau fabricated siv polydimethylsiloxane (PDMS).
Kev tshawb fawb: Ob-dimensional biocompatible plasma contact lo ntsiab muag rau kev kho xim dig muag.
Ntawm no, tus qauv tsim pheej yig rau kev kho cov xim liab-ntsuab qhov muag tsis pom kev tau tsim thiab sim ua raws li me me nanolithography.
Tib neeg cov xim kev nkag siab yog muab los ntawm peb lub cones zoo li photoreceptor hlwb, ntev (L), nruab nrab (M), thiab luv (S) cones, uas yog qhov tseem ceeb rau kev pom liab, ntsuab, thiab xiav tones, nrog spectral rhiab heev ntawm 430. , 530 thiab 560 nm.
Xim qhov muag tsis pom kev, tseem hu ua xim tsis pom kev tsis txaus (CVD), yog ib qho kab mob qhov muag uas cuam tshuam qhov kev tshawb pom thiab kev txhais cov xim sib txawv los ntawm peb lub hlwb photoreceptor uas ua haujlwm hauv qhov muag tsis pom kev thiab ua haujlwm raws li lawv cov spectral rhiab heev maxima.Cov kab mob qhov muag, uas tej zaum yuav yuav constrictive los yog caj ces, yog tshwm sim los ntawm ib tug poob los yog tsis xws luag nyob rau hauv lub cone photoreceptor hlwb.
Schematic daim duab ntawm cov txheej txheem fabrication ntawm lub proposed PDMS-raws li lens, (b) dluab ntawm fabricated PDMS-raws li lens, thiab (c) immersion ntawm PDMS-raws li lens nyob rau hauv HAuCl4 3H2O kub tov rau txawv incubation lub sij hawm.© Roostaei, N. thiab Hamidi, SM (2022)
Dichroism tshwm sim thaum ib qho ntawm peb lub khob cij photoreceptor cell tsis tuaj yeem ua tiav;thiab yog cais raws li proteophthalmia (tsis muaj liab cone photoreceptors), deuteranopia (tsis muaj ntsuab cone photoreceptors), los yog trichromatic xim dig muag (tsis muaj xiav cone photoreceptors).
Monochromaticity, qhov tsawg tshaj plaws ntawm cov xim qhov muag tsis pom kev, yog tus cwj pwm los ntawm qhov tsis muaj tsawg kawg yog ob lub cone photoreceptor cell hom.
Monochromatics yog tag nrho cov xim dig muag (colorblind) los yog tsuas muaj xiav lub khob hliav qab photoreceptors.Ib yam thib peb ntawm kev txawv txav trichromacy tshwm sim yog ib qho ntawm lub khob hliav qab photoreceptor cell malfunctions.
Aberrant trichromacy tau muab faib ua peb hom raws li hom cone photoreceptor defect: deuteranomaly (tsis zoo ntsuab cone photoreceptors), protanomaly (hloov liab cone photoreceptors), thiab tritanomaly (muaj teeb meem xiav cone photoreceptors) photoreceptor hlwb).
Protans (protanomaly thiab protanopia) thiab deutans (deuteranomaly thiab deuteranopia), feem ntau hu ua protanopia, yog hom kev ua tsis pom kev zoo tshaj plaws.
Protanomaly, lub spectral rhiab heev peaks ntawm liab cone hlwb yog xiav-hloov, thaum lub rhiab heev maxima ntawm ntsuab cone hlwb yog liab-hloov.Vim qhov teeb meem spectral rhiab heev ntawm ntsuab thiab liab photoreceptors, cov neeg mob tsis tuaj yeem paub qhov txawv ntawm qhov sib txawv.
Schematic daim duab ntawm cov txheej txheem fabrication ntawm lub tswv yim PDMS-raws li 2D plasmonic contact lens, thiab (b) cov duab tiag tiag ntawm fabricated 2D saj zawg zog plasmonic contact lens.© Roostaei, N. and Hamidi, SM (2022)
Txawm hais tias muaj ntau txoj haujlwm tseem ceeb hauv kev txhim kho kev kho tsis zoo rau qhov muag tsis pom xim raws li ntau txoj hauv kev kho mob rau tus mob no, kev hloov kho txoj kev ua neej tseem ceeb tseem muaj kev sib cav qhib.Gene therapy, tinted tsom iav, lo ntsiab muag, cov ntxaij lim dej kho qhov muag, tsom iav optoelectronic, thiab kev txhim kho ntawm cov khoos phis tawj thiab cov khoom siv mobile yog cov ncauj lus hais hauv kev tshawb fawb yav dhau los.
Tinted iav nrog cov xim lim tau raug tshawb fawb thiab pom tau tias muaj dav rau kev kho CVD.
Thaum cov iav no muaj kev vam meej hauv kev ua kom pom xim xim rau cov neeg dig muag xim, lawv muaj qhov tsis zoo xws li tus nqi siab, hnyav hnyav thiab ntau, thiab tsis muaj kev koom ua ke nrog lwm cov iav kho.
Rau kev kho CVD, lub ntsej muag tiv thaiv tau tsim siv cov tshuaj pigments, plasmonic metasurfaces, thiab plasmonic nanoscale hais tau raug tshawb xyuas tsis ntev los no.
Txawm li cas los xij, cov lo ntsiab muag no ntsib ntau yam teeb meem, suav nrog kev tsis muaj biocompatibility, kev siv tsawg, kev ruaj ntseg tsis zoo, tus nqi siab, thiab cov txheej txheem ntau lawm.
Txoj haujlwm tam sim no nthuav tawm ob-dimensional biocompatible thiab elastic plasmonic contact lo ntsiab muag raws li polydimethylsiloxane (PDMS) rau kev kho qhov muag tsis pom kev, nrog rau kev tshwj xeeb ntawm cov xim dig muag feem ntau, deuterochromatic anomaly (liab-ntsuab) xim dig muag.
PDMS yog biocompatible, saj zawg zog thiab pob tshab polymer uas tuaj yeem siv los ua cov lo ntsiab muag.Qhov no tsis muaj teeb meem thiab biocompatible tshuaj tau pom ntau yam kev siv hauv kev lag luam lom neeg, kev kho mob thiab tshuaj lom neeg.
Hauv kev ua haujlwm no, 2D biocompatible thiab elastic plasmonic contact lo ntsiab muag ua los ntawm PDMS, uas pheej yig thiab ncaj nraim rau kev tsim, tau tsim los siv ib qho me me nanoscale lithography mus kom ze, thiab kev kho deuteron raug sim.
Cov lo ntsiab muag yog tsim los ntawm PDMS, ib qho hypoallergenic, tsis muaj kev phom sij, elastic thiab pob tshab polymer.This plasmonic contact lens, raws li qhov tshwm sim ntawm plasmonic nto lattice resonance (SLR), tuaj yeem siv los ua cov xim zoo rau kev kho deuteron anomalies.
Cov ntaub ntawv lo ntsiab muag muaj cov khoom zoo xws li durability, biocompatibility thiab elasticity, ua rau lawv haum rau kev kho qhov muag tsis pom xim.
Post lub sij hawm: Jun-23-2022
